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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
9.7
Human Site:
S285
Identified Species:
15.24
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S285
K
P
G
P
P
P
Q
S
K
P
N
S
S
F
R
Chimpanzee
Pan troglodytes
XP_510301
627
67581
S264
G
Q
L
P
G
R
S
S
P
A
G
S
P
R
T
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
N285
K
P
G
P
P
P
Q
N
K
P
N
S
S
F
R
Dog
Lupus familis
XP_544614
968
105825
S572
K
P
G
P
P
S
Q
S
K
P
N
S
S
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
N286
K
P
V
P
L
P
Q
N
K
P
N
S
A
F
R
Rat
Rattus norvegicus
Q62829
544
60692
E181
E
D
E
E
E
E
E
E
E
D
D
N
E
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
P276
R
P
P
Q
D
S
S
P
V
P
A
A
K
A
Q
Chicken
Gallus gallus
XP_426393
667
74767
G285
F
F
R
P
Q
Q
W
G
S
P
R
S
P
A
A
Frog
Xenopus laevis
NP_001082100
650
73749
S280
P
R
A
E
T
D
P
S
R
G
A
A
H
Q
V
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S285
N
S
P
G
R
P
F
S
S
Y
D
L
K
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q276
Y
P
T
S
H
Q
Q
Q
Q
Q
Q
Q
Q
Q
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
S261
L
Q
I
F
D
T
S
S
K
D
Q
Q
I
T
Q
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P209
N
E
N
R
S
S
M
P
P
S
Y
A
P
P
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T436
F
N
K
F
P
P
S
T
S
D
S
H
N
Y
G
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
A434
L
Q
T
G
V
G
Y
A
H
G
P
M
S
P
M
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
20
93.3
93.3
N.A.
73.3
0
N.A.
13.3
20
6.6
13.3
N.A.
13.3
13.3
0
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
33.3
N.A.
33.3
20
20
20
N.A.
20
20
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
7
0
7
14
20
7
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
14
7
0
0
0
20
14
0
0
0
7
% D
% Glu:
7
7
7
14
7
7
7
7
7
0
0
0
7
0
0
% E
% Phe:
14
7
0
14
0
0
7
0
0
0
0
0
0
27
0
% F
% Gly:
7
0
20
14
7
7
0
7
0
14
7
0
0
0
7
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
7
7
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
27
0
7
0
0
0
0
0
34
0
0
0
14
0
0
% K
% Leu:
14
0
7
0
7
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% M
% Asn:
14
7
7
0
0
0
0
14
0
0
27
7
7
0
0
% N
% Pro:
7
40
14
40
27
34
7
14
14
40
7
0
20
20
14
% P
% Gln:
0
20
0
7
7
14
34
7
7
7
14
14
7
14
14
% Q
% Arg:
7
7
7
7
7
7
0
0
7
0
7
0
0
7
27
% R
% Ser:
0
7
0
7
7
20
27
40
20
7
7
40
27
7
0
% S
% Thr:
0
0
14
0
7
7
0
7
0
0
0
0
0
7
7
% T
% Val:
0
0
7
0
7
0
0
0
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
0
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _